Michelle Lynn Oyen

Reader in Bioengineering, Cambridge University Engineering Dept.

Fellow and Director of Studies, Homerton College, Cambridge


  • Cambridge University, M.A., July, 2010.
  • University of Minnesota, Ph.D. in Biophysical Sciences and Medical Physics, June, 2005. (GPA 3.82/4.00) Dissertation title: “Ultrastructural Characterization of Time-Dependent, Inhomogeneous Materials and Tissues”.
  • Michigan State University, M. S. in Engineering Mechanics, December, 1998. (GPA 3.95/4.00)
  • Michigan State University, B. S. in Materials Science and Engineering, May, 1996. (GPA 3.95/4.00)
  • Osseo Senior High School, June, 1993



Michelle’s Google Scholar page

  1. Oyen-Tiesma M, Atkinson J, and Haut RC, A Method for Promoting Regular Exercise in Rabbits Involved in Orthopaedics Research, Contemporary Topics in Laboratory Animal Research, 37 (1998) 77-80. [link]
  2. Atkinson PJ, Oyen-Tiesma M, DeCamp CE, Mackenzie CD, and Haut RC, Patellar Tendon Augmentation After Removal of its Central Third Limits Joint Tissue Changes, Journal of Orthopaedic Research, 17 (1999) 28-36. [link]
  3. Oyen-Tiesma M, and Cook RF, Technique for Estimating the Fracture Resistance of Cultured Neocartilage, Journal of Materials Science: Materials in Medicine, 12 (2001) 327-332. [link]
  4. Oyen ML and Cook RF, Load-Displacement Behavior During Sharp Indentation of Viscous-Elastic-Plastic Materials>, Journal of Materials Research, 18 (2003) 139-50. [link]
  5. Lewis JL, Deloria LB, Oyen-Tiesma M, Thompson RC, Ericson M, and Oegema TR, Cell Death After Cartilage Impact Occurs Around Matrix Cracks, Journal of Orthopaedic Research, 21 (2003) 881-7. [ link]
  6. Oyen ML, Calvin SE, and Cook RF, Uniaxial Stress-Relaxation and Stress-Strain Responses of Human Amnion, Journal of Materials Science: Materials in Medicine, 15 (2004) 619-24. [link]
  7. Oyen ML, Cook RF, and Calvin SE, Mechanical Failure of Human Fetal Membrane Tissues, Journal of Materials Science: Materials in Medicine, 15 (2004) 651-8. [link]
  8. Oyen ML, Cook RF, Moody NR, and Emerson JA, Indentation Responses of Time-Dependent Films on Stiff Substrates, Journal of Materials Research, 19 (2004) 2487-97. Erratum in Journal of Materials Research, 19 (2004) 3120-1. [link]
  9. Oyen ML, Spherical Indentation Creep Following Ramp Loading, Journal of Materials Research, 20 (2005) 2094-2100. [link]
  10. Oyen ML, Cook RF, Stylianopoulos T, Barocas VH, Calvin SE, and Landers DL, Uniaxial and Biaxial Mechanical Behavior of Human Amnion. Journal of Materials Research, 20 (2005) 2902-9. [link]
  11. Oyen ML and Ko C-C, Examination of Local Variations in Viscous, Elastic, and Plastic Indentation Responses in Healing Bone, Journal of Materials Science: Materials in Medicine, 18 (2007) 623-8. [link]
  12. Oyen ML, Nanoindentation Hardness Measurements of Mineralized Tissues, Journal of Biomechanics, 39 (2006) 2699-702. [link]
  13. Oyen ML, Calvin SE, and Landers DV, Premature rupture of the fetal membranes: Is the Amnion the Major Determinant? American Journal of Obstetrics and Gynecology, 195 (2006) 510-515. [link]
  14. Bembey AK, Oyen ML, Bushby AJ, Boyde A, Viscoelastic properties of bone as a function of hydration state determined by nanoindentation. Philosophical Magazine, 86(33-35) (2006) 5691 – 5703. [link]
  15. Oyen ML, Analytical Techniques for Indentation of Viscoelastic Materials, Philosophical Magazine 86(33-35) (2006) 5625 – 5641. [link]
  16. Bembey AK, Bushby AJ, Boyde A, Ferguson VL, Oyen ML, Hydration Effects on the Micro-Mechanical Properties of Bone. Journal of Materials Research, 21 (2006) 1962-8. [link]
  17. Mattice JM, Lau AG, Oyen ML, Kent RW, Spherical Indentation Load-Relaxation of Soft Biological Tissues, Journal of Materials Research 21 (2006) 2003-10. [link]
  18. Ko C-C, Oyen ML, Fallgatter AM, Kim J-H, Douglas WH, Fricton J, Hu W-S, Mechanical Properties and Cytocompatibility of Biomimetic Hydroxyapatite-Gelatin Nano-Composites, Journal of Materials Research, 21 (2006) 3090-8. [link]
  19. Bass CR, Lucas SR, Salzar RS, Oyen ML, Planchak C, Shender BS, Paskoff G, Failure properties of cervical spinal ligaments under fast strain rate deformations. Spine 32 (2007) E7-E13. [link]
  20. (invited review) Oyen ML and Bushby AJ, Viscoelastic Effects in Small-Scale Indentation of Biological Materials. International Journal of Surface Science and Engineering, 1 (2007) 180-197. [link]
  21. Cook RF and Oyen ML, Nanoindentation behavior and mechanical properties measurement of polymeric materials. International Journal of Materials Research, 98 (2007) 370-8.
  22. Oyen ML, Sensitivity of Polymer Nanoindentation Creep Properties to Experimental Variables, Acta Materialia. 55 (2007) 3633-9. [link]
  23. Calvin SE and Oyen ML, Microstructure and Mechanics of the Chorioamnion Membrane with an Emphasis on Fracture Properties. Annals of the New York Academy of Sciences 1101 (2007) 166–185. [link]
  24. Lau AG, Oyen ML, Kent RW, Murakami D, Torigaki T, Indentation Stiffness of Aging Human Costal Cartilage. Acta Biomaterialia 4 (2008) 97-103. [link]
  25. Lucas SR, Bass CR, Salzar RS, Oyen ML, Planchak C, Ziemba A, Shender BS, Paskoff G. Viscoelastic properties of the cervical spine under fast strain rate deformations. Acta Biomaterialia 4 (2008) 117-25. [link]
  26. Oyen ML and Ko CC, Indentation Variability of Natural Nanocomposite Materials, Journal of Materials Research 23 (2008) 760-7. [link]
  27. (invited) Oyen ML, The Materials Science of Bone: Lessons from Nature for Biomimetic Materials Synthesis. Materials Research Society Bulletin 33 (2008) 49-55. [link]
  28. Oyen ML, Poroelastic Nanoindentation Responses of Hydrated Bone. Journal of Materials Research 23 (2008) 1307-14. [link]
  29. Oyen ML, Relating Viscoelastic Nanoindentation Creep and Load Relaxation Experiments, International Journal of Materials Research 99 (2008) 823-8.
  30. Oyen ML, Ferguson VL, Bembey AK, Bushby AJ, Boyde A. Composite Bounds on the Elastic Modulus of Bone. Journal of Biomechanics 41 (2008) 2585-88. [ link]
  31. Galli M and Oyen ML, Spherical Indentation of a Finite Poroelastic Coating. Applied Physics Letters 93 (2008) 031911. [link]
  32. Oyen ML and Cook RF. A Practical Guide for Analysis of Nanoindentation Data. Journal of the Mechanical Behavior of Biomedical Materials 2 (2008) 396-407. [link]
  33. Hauch KN, Oyen ML, Odegard GM, Haut Donahue TL. Nanoindentation of the Insertional Zones of Human Meniscal Attachments into Underlying Bone. Journal of the Mechanical Behavior of Biomedical Materials 2 (2008) 339-47. [link]
  34. Galli M, Comley KSC, Shean TAV, Oyen ML. Viscoelastic and Poroelastic Mechanical Characterization of Hydrated Gels. Journal of Materials Research 24 (2009) 973-9. [link]
  35. Chua W and Oyen ML. Do we know the strength of the chorioamnion? A critical review and analysis. European Journal of Obstetrics & Gynecology and Reproductive Medicine 144 Supp. 1 (2009) S128-S133. [link]
  36. Galli M and Oyen ML. Creep properties from indentation tests by analytical and numerical techniques. International Journal of Materials Research 100 (2009) 954-9. [link]
  37. Chua W and Oyen ML. Viscoelastic Properties of Membranes Measured by Spherical Indentation, Cellular and Molecular Bioengineering 2 (2009) 49-56. [link]
  38. Gentleman E, Swain RJ, Evans ND, Jell G, Ball MD, Boonrungsiman S, Shean TAV, Oyen ML, Porter A, Stevens MM, Comparative materials differences revealed in engineered bone as a function of cell-specific differentiation, Nature Materials 8 (2009) 763-70. [link]
  39. Galli M and Oyen ML, Fast Identification of Poroelastic Parameters from Indentation Tests. CMES (Comp. Modeling Eng. Sci.) 48 (2009) 241 − 268. [pdf file]
  40. Olesiak SE, Oyen ML, Ferguson VL, Viscous-Elastic-Plastic Behavior of Bone using Berkovich Nanoindentation. Mech. Time-Dependent Mater. (2009) in press. [link]
  41. Olesiak SE, Sponheimer M, Eberle J, Oyen ML, Ferguson VL, Nanomechanical properties of modern and fossil bone. Palaeogeography, Palaeoclimatology, Palaeoecology 289 (2010)
    25 − 32.
  42. Gwynne JH, Oyen ML, Cameron RE, Preparation of Polymeric Samples Containing a Graduated Modulus Region and Development of Nanoindentation Linescan Techniques. Polymer Testing 29 (2010) 494 − 502.
  43. VanLeene M, Saldanha Z, Cloyd KL, Jell G, Bou-Gharios G, Duncan Bassett JH, Williams GR, Fisk NM, Oyen ML, Stevens MM, Guillot PV, Shefelbine SJ, Transplantation of Human Fetal Blood Mesenchymal Stem/Stromal Cells in the Osteogenesis Imperfecta Murine (Oim) Mouse Leads To Improvement in Multi-Scale Tissue Properties via Osteoblast Differentiation of Donor Cells and Production of Normal Collagen. Blood 117 (2011) 1053 − 60.
  44. (Invited Review) Oyen ML, Nanoindentation of Biological and Biomimetic Materials, Experimental Techniques 37 (2013) 73-87.
  45. Galli M, Fornasiere E, Cugnoni J and Oyen ML, Poroviscoelastic Characterization of Particle-Reinforced Gelatin Gels Using Indentation and Homogenization. J. Mech. Behav. Biomed. Mater. 4 (2011) 610-7.
  46. Qiang B, Greenleaf J, Oyen ML, Zhang X, Estimation of Material Elasticity by Spherical Indentation Load-relaxation Tests on Viscoelastic Samples of Finite Thickness, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 57 (2011) 1418-29.
  47. Strange DGT and Oyen ML, Biomimetic Bone-Like Composites Fabricated Through an Automated Alternate Soaking Process, Acta Biomaterialia 7 (2011) 3586-94.
  48. Oyen ML, Shean TAVS, Strange DGT, Galli M, Size Effects in Indentation of Hydrated Biological Tissues, Journal of Materials Research 27 (2012) 245-55.
  49. Cottenden DJ and Oyen ML, Quantitative modelling of viscoelasticity of isotropic fibrous composites with viscoelastic matrices. Applied Mechanics Letters 1 (2011) 052006.
  50. Strange DGT and Oyen ML, Composite Hydrogels for Nucleus Pulposus Tissue Engineering. J. Mech. Behav. Biomed. Mater. 11 (2012) 16-26.
  51. Vanleene M, Porter AE, Guillot P-V, Boyde A, Oyen ML, Shefelbine SJ, Ultra-Structural Defects Cause Low Bone Matrix Stiffness Despite High Mineralization in Osteogenesis Imperfecta Mice Bone. Bone 50 (2012) 1317-23.
  52. Koh CT and Oyen ML, Branching Toughens Fibrous Networks. J. Mech. Behav. Biomed. Mater. 12 (2012) 74-82.
  53. Koh CT and Oyen ML, Fracture Toughness of Fibrous Membranes. Technische Mechanik 32 (2012) 333-41.
  54. Trappmann B, Gautrot JE, Connelly JT, Strange DGT, Li Y, Oyen ML, Cohen Stuart MA, Boehm H, Li B, Vogel V, Spatz JP, Watt FM, Huck WTS, Extracellular-matrix tethering regulates stem-cell fate. Nature Materials 11 (2012) 642-9.
  55. Finnemore A, Cunha P, Shean T, Vignolini S, Guldin S, Oyen M and Steiner U, Biomimetic layer-by-layer assembly of artificial nacre. Nature Communications 3 (2012) article 966, doi: 10.1038/ncomms1970.
  56. Armitage OE, Strange DGT, Oyen ML, Biomimetic Calcium Carbonate-Gelatin Composites as a Model System for Eggshell Mineralization. Journal of Materials Research 27 (2012) 3157-64.
  57. Rodriguez N, Oyen ML, Shefelbine SJ, Insight into Differences in Nanoindentation Properties of Bone, J. Mech. Behav. Biomed. Mater. 18 (2013) 90-99.
  58. Strange DGT, Fletcher TL, Tonsomboon K, Brawn H, Zhao X, Oyen ML, Separating poroviscoelastic deformation mechanisms in hydrogels. Applied Physics Letters 102, (2013) 031913.
  59. (Invited Review) Shapiro JM and Oyen ML, Hydrogel Composite Materials for Tissue Engineering Scaffolds, JOM 65 (2013) 505-516.
  60. Koh CT, Strange DGT, Tonsomboon K, Oyen ML, Failure Mechanisms in Fibrous Scaffolds, Acta Biomaterialia 9 (2013) 7326–7334.
  61. Tonsomboon K, Oyen ML, Composite Electrospun Gelatin Fiber-Alginate Gel Scaffolds for Mechanically Robust Tissue Engineered Cornea, J. Mech. Behav. Biomed. Mater. 21 (2013) 185–194.
  62. (Invited Review) Oyen ML, Mechanical Characterization of Hydrogel Materials, International Materials Reviews (2013) in press.


  • NRC Post-doctoral fellowship, 2006 (declined).
  • MRS Trophy Award for Best Proceedings Paper, 2005.
  • ASME-IMECE Bioengineering Division Student Paper Contest 2nd Place Award, 2004.
  • Society for Experimental Mechanics Student Paper Contest 3rd Place Award, 2001.
  • National Science Foundation Graduate Research Fellowship, awarded Spring, 1996.
  • Society of Women Engineers Scholarship Awards, 1995 and 1996.
  • MSU College of Engineering Academic Achievement Awards, 1994, 1995, and 1996.


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Edited Volume


Copyright © 2013, Michelle L. Oyen

Revised: June 28, 2013